About the Role:

Stylus Medicine is seeking an Associate Scientist, Automation to join our Genome Sciences & Engineering team and build automation capabilities that accelerate the development of our next-generation gene editing tools. This role is ideal for a collaborative, organized, and creative scientist who thrives in a fast-paced environment and enjoys tackling complex problems to expand the frontiers of genome editing. This individual will play a key role in discovery and engineering efforts, advancing recombinase-based genome editing platforms and collaborating across diverse R&D teams.

Key Responsibilities & Accountabilities:

• Develop automation capabilities that support reagent generation and high-throughput (HT) screening workflows

• Optimize automated HT workflows for plasmid cloning and RNA generation via in vitro transcription (IVT)

• Develop and run QC assays to sequence-verify plasmid constructs and assess the integrity of IVT products

• Partner with screening scientists to automate plate preparation, reagent dispensing, and assay setup for cell-based HT screens

• Coordinate DNA synthesis and reagent orders with external vendors

• Manage raw material, plasmid, and RNA inventories

• Maintain detailed documentation of protocols, methods, and results in electronic lab notebooks

• Present findings clearly to other teams and contribute to scientific discussions and decision-making

Qualifications & Skills:

• BS with 5+ years or MS with 2+ years of full-time industry or academic research experience in life sciences, biology, biochemistry, engineering, or a related field

• Experience with automated liquid handling systems (e.g., Biomek, Mantis, Echo) and high-throughput laboratory workflows, including method development and troubleshooting

• Familiarity with automating cell-based screening workflows; experience with flow cytometry is a plus

• Proficiency in nucleic acid QC methods, including TapeStation, Qubit, NanoDrop, and qPCR

• Hands-on molecular biology experience, including cloning and RNA production and purification

• Working knowledge of data analysis and information management tools such as Excel, GraphPad Prism, SnapGene, and Benchling

• Experience with laboratory inventory management

• Track record of generating precise, reproducible data and performing rigorous quantitative analysis

• Clear and approachable communication skills, with the ability to present technical information clearly and concisely to diverse audiences

• Exceptionally organized and comfortable managing large sample sets, inventories, and overlapping projects

• Strategic thinker who effectively plans and prioritizes to maximize scientific impact

• Collaborative mindset with a team-first attitude

• Resourceful problem-solver who enjoys troubleshooting instruments and workflows and thrives amid scientific uncertainty

Pay Range: $105,000 - $120,000